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An experimental study on the tissue reaction of toothash implanted in mandible body of the mature dog

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Abstract


The purpose of study is to evaluate whether the ashed toooth powder is utilized as an alternative material of the implant. For this purpose the author performed the experimental study to investigate the tissue response of sintered toothash and
its
histocompatibility.
Bony defects to expose the body of marrow, 1¡¿1cm in size, were creasted in the right nd left mandibular body of mature dog, and then the ashed tooth powderrs were filled in right side and the blood clot was filled in the left side as an control.
The dogs were sacrificed at 4th, 7th, and 16th week after implantation and histologic examination was performed.
@ES The results of this study were obtained as follows:
@EN 1. any inflammatory response was not noted after implanting of the ashed tooth powder during the whole experimental period.
2. At 4th week, ashed tooth powders were surrounded by mature connective tissue. And we could observe hydroxyapatite crystal structure within the ashed tooth powder.
3. At 7th week, we cou7ld observe that macrophage phagocyted the small granules of ashed tooth powders.
4. At 16th week, the union with host bone by growth of new trabeculae was observed. And there were remnants of ashed tooth power within some of new trabeculae.

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